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太赫兹波对肾癌组织的光谱检测

李晗,  余晨

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文章导航 > 红外与激光工程  > 2016 >  45(5): 525001-0525001(5)
李晗, 余晨. 太赫兹波对肾癌组织的光谱检测[J]. 红外与激光工程, 2016, 45(5): 525001-0525001(5). doi: 10.3788/IRLA201645.0525001
引用本文: 李晗, 余晨. 太赫兹波对肾癌组织的光谱检测[J]. 红外与激光工程, 2016, 45(5): 525001-0525001(5). doi: 10.3788/IRLA201645.0525001
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Li Han, Yu Chen. Terahertz spectral detection in human renal tissue[J]. Infrared and Laser Engineering, 2016, 45(5): 525001-0525001(5). doi: 10.3788/IRLA201645.0525001
Citation: Li Han, Yu Chen. Terahertz spectral detection in human renal tissue[J]. Infrared and Laser Engineering, 2016, 45(5): 525001-0525001(5). doi: 10.3788/IRLA201645.0525001
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太赫兹波对肾癌组织的光谱检测

doi: 10.3788/IRLA201645.0525001
  • 1.

    上海市第一康复医院,上海 200090;

  • 2.

    同济大学附属同济医院,上海 200065

详细信息
    作者简介:

    李晗(1983-),女,硕士生,主要从事慢性肾脏病患者的康复治疗技术及肾脏肿瘤及纤维化新技术研究方面的研究。Email:April_hanhanli@hotmail.com

  • 中图分类号: O433.4

Terahertz spectral detection in human renal tissue

  • 1.

    The First Rehabilitation Hospital of Shanghai,Shanghai 200090,China;

  • 2.

    Tongji Hospital Affiliated to Tongji University,Shanghai 200065,China

  • 摘要: 利用太赫兹光谱技术,对人肾癌组织进行检测,分别比较了肿瘤组织和肿瘤旁正常组织对太赫兹波的响应。通过对新鲜含水和经冷冻真空脱水组织的测量分析,分别获得了不同样品在0.2~1.2 THz波段的吸收系数和折射率。结果显示,生物组织中含水量对太赫兹波吸收信号强度有很大的影响。同时,不同组织的细胞结构和成分也是影响太赫兹信号强度的重要因素。比如癌细胞和正常细胞的结构的不同,因此对太赫兹电磁波的吸收以及它们在太赫兹波段的折射率都有显著的不同。结果显示太赫兹光谱技术在生物组织检测和临床医学如肿瘤疾病诊断方面具有广阔的应用前景。
    Abstract: In this paper, terahertz spectroscopy technique was used for the investigation of human renal cancer by comparing the response of tumor tissue and normal tissue adjacent to tumor. Based on the measurement and analysis of fresh tissue and lyophilized tissue respectively, the absorption coefficient and refractive index from 0.2 THz to 1.2 THz were obtained. The result shows that water content of biological tissue has great influence on terahertz wave absorption signal amplitude. Meanwhile, difference of cell structure and composition also affect the transmission of terahertz signal. For example, as the different structure and composition of the cancer and normal cell, the absorption coefficient and refractive index of these tissues are completely different. The result indicates that terahertz spectroscopy technique is an important technology and has a broad prospect of application in biological tissue investigation and clinical medicine such as tumor disease diagnosis.
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出版历程
  • 收稿日期:  2016-03-15
  • 修回日期:  2016-04-12
  • 刊出日期:  2016-05-25

太赫兹波对肾癌组织的光谱检测

doi: 10.3788/IRLA201645.0525001
  • 1. 上海市第一康复医院,上海 200090;
  • 2. 同济大学附属同济医院,上海 200065
    • 作者简介:

    李晗(1983-),女,硕士生,主要从事慢性肾脏病患者的康复治疗技术及肾脏肿瘤及纤维化新技术研究方面的研究。Email:April_hanhanli@hotmail.com

  • 收稿日期: 2016-03-15
  • 修回日期: 2016-04-12
  • 刊出日期: 2016-05-25

  • 中图分类号: O433.4

摘要: 利用太赫兹光谱技术,对人肾癌组织进行检测,分别比较了肿瘤组织和肿瘤旁正常组织对太赫兹波的响应。通过对新鲜含水和经冷冻真空脱水组织的测量分析,分别获得了不同样品在0.2~1.2 THz波段的吸收系数和折射率。结果显示,生物组织中含水量对太赫兹波吸收信号强度有很大的影响。同时,不同组织的细胞结构和成分也是影响太赫兹信号强度的重要因素。比如癌细胞和正常细胞的结构的不同,因此对太赫兹电磁波的吸收以及它们在太赫兹波段的折射率都有显著的不同。结果显示太赫兹光谱技术在生物组织检测和临床医学如肿瘤疾病诊断方面具有广阔的应用前景。

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