偏振成像系统中的面阵CMOS传感器非线性校正

付轶帆; 吴剑; 何宏辉

doi:10.3788/IRLA201645.0633001

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偏振成像系统中的面阵CMOS传感器非线性校正

付轶帆, 吴剑, 何宏辉

文章导航 > 红外与激光工程 > 2016 > 45(6): 633001-0633001(5)

付轶帆, 吴剑, 何宏辉. 偏振成像系统中的面阵CMOS传感器非线性校正[J]. 红外与激光工程, 2016, 45(6): 633001-0633001(5). doi: 10.3788/IRLA201645.0633001

引用本文:

付轶帆, 吴剑, 何宏辉. 偏振成像系统中的面阵CMOS传感器非线性校正[J]. 红外与激光工程, 2016, 45(6): 633001-0633001(5). doi: 10.3788/IRLA201645.0633001

Fu Yifan, Wu Jian, He Honghui. Non-linear correction of area CMOS sensor in polarization imaging system[J]. Infrared and Laser Engineering, 2016, 45(6): 633001-0633001(5). doi: 10.3788/IRLA201645.0633001

Citation:

Fu Yifan, Wu Jian, He Honghui. Non-linear correction of area CMOS sensor in polarization imaging system[J]. Infrared and Laser Engineering, 2016, 45(6): 633001-0633001(5). doi: 10.3788/IRLA201645.0633001

偏振成像系统中的面阵CMOS传感器非线性校正

doi: 10.3788/IRLA201645.0633001

1.
清华大学深圳研究生院生物医学工程研究所,广东深圳 518055;
2.
清华大学深圳研究生院深圳市无损监测与微创医学技术重点实验室,广东深圳 518055

基金项目:

深圳市基础研究计划(JCY20130402145002404)

详细信息

作者简介:
付轶帆(1987-),男,博士生,主要从事医学图像处理、三维重建、偏振内窥方面的研究。Email:fuyf14@mails.tsinghua.edu.cn

中图分类号: TP212

Non-linear correction of area CMOS sensor in polarization imaging system

1.
Institute of Biomedical Engineering,Graduate School at Shenzhen,Tsinghua University,Shenzhen 518055,China;
2.
Shenzhen Key Laboratory for Minimal Invasive Medical Technologies,Graduate School at Shenzhen,Tsinghua University,Shenzhen 518055,China

摘要: mueller矩阵偏振成像可用于获取生物组织的浅表层生理学信息,在疾病早期诊断与预防中具有重要意义。而在偏振成像系统中直接使用商用面阵CMOS相机不能得到用于解算mueller矩阵的正确图像信息,限制了其在小型化内窥领域上的应用。对商用面阵CMOS的研究表明其光信号输入输出呈非线性映射关系。综合考虑到传感器固有的成像噪声,提出一种基于校正的方法对CMOS的输出数据进行映射以获取正确的组织偏振信息值。实验结果表明校正后的偏振信息可以解算得到正确的mueller矩阵值,误差可以控制在3%以内,对蚕丝样品的测试也证明了该方法的有效性。上述结果使得内窥探头上应用小型化的商用面阵CMOS图像传感器进行体内生物组织mueller矩阵测量成为可能。
- 非线性校正 /
- 面阵CMOS /
- mueller矩阵 /
- 内窥
Abstract: Polarization imaging with mueller matrix can be used to obtain the physiological information of superficial biological tissue, which has significant importance in early diagnosis and prevention of cancerous disease. However, the mueller matrix deduced by the polarization information collected from the commercial CMOS sensor directly is not correct, which limits the application of commercial micro CMOS sensor in the endoscopic imaging. The study on commercial area CMOS sensor indicates its non-linear input to output mapping relationship for sensed light intensity. Considering the inherent background noise, a calibration-based method was proposed to mapping the output of the CMOS sensor to obtain the correct polarization information for tested samples. Experiment results demonstrate that the correct mueller matrix can be deduced according to the corrected polarization information, and the error compared to the standard air mueller matrix is below 3%. The effectiveness of this method is demonstrated by the experiment implemented on silk sample. The results of the proposed method reveal the possibility to apply commercial micro CMOS sensor on the endoscopic tip for in vivo biological tissue mueller matrix measurement.
- non-linear correction /
- area CMOS sensor /
- mueller matrix /
- endoscopic

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偏振成像系统中的面阵CMOS传感器非线性校正

doi: 10.3788/IRLA201645.0633001

1. 清华大学深圳研究生院生物医学工程研究所,广东深圳 518055;

2. 清华大学深圳研究生院深圳市无损监测与微创医学技术重点实验室,广东深圳 518055

作者简介:
付轶帆(1987-),男,博士生,主要从事医学图像处理、三维重建、偏振内窥方面的研究。Email:fuyf14@mails.tsinghua.edu.cn

收稿日期: 2015-10-05
修回日期: 2015-11-03
刊出日期: 2016-06-25

基金项目:

深圳市基础研究计划(JCY20130402145002404)

中图分类号: TP212

关键词:

摘要: mueller矩阵偏振成像可用于获取生物组织的浅表层生理学信息,在疾病早期诊断与预防中具有重要意义。而在偏振成像系统中直接使用商用面阵CMOS相机不能得到用于解算mueller矩阵的正确图像信息,限制了其在小型化内窥领域上的应用。对商用面阵CMOS的研究表明其光信号输入输出呈非线性映射关系。综合考虑到传感器固有的成像噪声,提出一种基于校正的方法对CMOS的输出数据进行映射以获取正确的组织偏振信息值。实验结果表明校正后的偏振信息可以解算得到正确的mueller矩阵值,误差可以控制在3%以内,对蚕丝样品的测试也证明了该方法的有效性。上述结果使得内窥探头上应用小型化的商用面阵CMOS图像传感器进行体内生物组织mueller矩阵测量成为可能。

English Abstract

Non-linear correction of area CMOS sensor in polarization imaging system

1. Institute of Biomedical Engineering,Graduate School at Shenzhen,Tsinghua University,Shenzhen 518055,China;

2. Shenzhen Key Laboratory for Minimal Invasive Medical Technologies,Graduate School at Shenzhen,Tsinghua University,Shenzhen 518055,China

Received Date: 2015-10-05
Rev Recd Date: 2015-11-03
Publish Date: 2016-06-25

Keywords:

Abstract: Polarization imaging with mueller matrix can be used to obtain the physiological information of superficial biological tissue, which has significant importance in early diagnosis and prevention of cancerous disease. However, the mueller matrix deduced by the polarization information collected from the commercial CMOS sensor directly is not correct, which limits the application of commercial micro CMOS sensor in the endoscopic imaging. The study on commercial area CMOS sensor indicates its non-linear input to output mapping relationship for sensed light intensity. Considering the inherent background noise, a calibration-based method was proposed to mapping the output of the CMOS sensor to obtain the correct polarization information for tested samples. Experiment results demonstrate that the correct mueller matrix can be deduced according to the corrected polarization information, and the error compared to the standard air mueller matrix is below 3%. The effectiveness of this method is demonstrated by the experiment implemented on silk sample. The results of the proposed method reveal the possibility to apply commercial micro CMOS sensor on the endoscopic tip for in vivo biological tissue mueller matrix measurement.

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偏振成像系统中的面阵CMOS传感器非线性校正

doi: 10.3788/IRLA201645.0633001

作者简介: 付轶帆(1987-),男,博士生,主要从事医学图像处理、三维重建、偏振内窥方面的研究。Email:fuyf14@mails.tsinghua.edu.cn

Non-linear correction of area CMOS sensor in polarization imaging system

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出版历程

偏振成像系统中的面阵CMOS传感器非线性校正

doi: 10.3788/IRLA201645.0633001

1. 清华大学 深圳研究生院 生物医学工程研究所,广东 深圳 518055; 2. 清华大学 深圳研究生院 深圳市无损监测与微创医学技术重点实验室,广东 深圳 518055

作者简介: 付轶帆(1987-),男,博士生,主要从事医学图像处理、三维重建、偏振内窥方面的研究。Email:fuyf14@mails.tsinghua.edu.cn

English Abstract

Non-linear correction of area CMOS sensor in polarization imaging system

1. Institute of Biomedical Engineering,Graduate School at Shenzhen,Tsinghua University,Shenzhen 518055,China; 2. Shenzhen Key Laboratory for Minimal Invasive Medical Technologies,Graduate School at Shenzhen,Tsinghua University,Shenzhen 518055,China

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目录

作者简介:
付轶帆(1987-),男,博士生,主要从事医学图像处理、三维重建、偏振内窥方面的研究。Email:fuyf14@mails.tsinghua.edu.cn

1. 清华大学深圳研究生院生物医学工程研究所,广东深圳 518055;

2. 清华大学深圳研究生院深圳市无损监测与微创医学技术重点实验室,广东深圳 518055

作者简介:
付轶帆(1987-),男,博士生,主要从事医学图像处理、三维重建、偏振内窥方面的研究。Email:fuyf14@mails.tsinghua.edu.cn

1. Institute of Biomedical Engineering,Graduate School at Shenzhen,Tsinghua University,Shenzhen 518055,China;

2. Shenzhen Key Laboratory for Minimal Invasive Medical Technologies,Graduate School at Shenzhen,Tsinghua University,Shenzhen 518055,China