Abstract: A longitudinal microstructured fiber based sensing scheme was proposed, the sensing capacity of which was greatly expanded by using frequency and wavelength encode simultaneously. Quasi-distributed pressure measurement along a single fiber was achieved, showing potential of high capacity multiplexing, high spatial resolution and high accurate detection. The silicone rubber package of sensing fiber made the pressure sensitivity increased to 1.03210-3 relative wavelength shift/MPa, which is 500 times higher than bare FBG. Experimental results of the prototype system including 6 fiber microstructures exhibited good linearity and relatively high measurement accuracy. High Resolution Manometry(HRM) in long distance based on this scheme is promising, which can be widely used in civil structural health monitoring, pipeline leakage detecting and distributed pressure sensing for in-vivo.