Abstract: The environmental tolerance of infrared detectors depends on complete and effective environmental tolerance measures in design and manufacturing. The environmental test and evaluation of infrared detectors verify the ability to work normally in extreme environments. The purpose of the test at each stage of development, production and use is different, and the amount of stress applied by the test is different. It is necessary to measure the natural conditions and inducing conditions, and to analyse the investigation of temperature response characteristics and test environment. According to the measure and the analysis, to select the correct, reasonable and necessary design and test environmental conditions collect the most suitable test data as much as possible, to ensure the quality level required by customers and the availability of competitive prices. The temperature response test measured data of 288×4 infrared focal plane Dewar module and time constant method were used to calculate and analyze the temperature stabilization time. The results showed that, in the temperature cycles screening and erature shock test, a sudden temperature change stress greater than 10 ℃/min could not impose on the functional parts of the infrared detector, and the defect screening effect of the cold head part was better when the temperature change rate of the high temperature working state was greater than 50 ℃/min. The test results indicate that the stress for vacuum integrity is greater than +90 ℃ for 2160 h in the vacuum integrity constant high temperature test. The products passed the failure-free environmental test assessment at high-temperature +71 ℃ and low-temperature −54 ℃ have the potential to be stored, transported and used all over the world.