Abstract: In recent years, the emergence and rapid development of tunable mid-infrared new-band ultra-intense ultrashort lasers have opened up a parametric space in the field of strong-field physics that has rarely been explored so far, providing new opportunities to explore new physics, new effects and new applications of ultra-intense ultrashort laser-matter interactions. The development trends and research directions of mid-infrared ultra-intense ultrashort lasers in recent years were summarized in this paper. The four research directions of optical parametric amplification, optical parametric chirp pulse amplification, mid-infrared pulse post-compression and new optical field modulation technology in mid-infrared were analyzed in a comprehensive manner, and the future development trend of mid-infrared ultra-intense ultrashort lasers was also prospected.