Abstract: High efficiency and quality is the main focus direction within the laser cleaning area, and also the key to realize the large-scale industrial application. The National Key Research and Development Program "Additive Manufacturing and Laser Manufacturing" Key Special Project "High Energy High Repetition Rate Pulsed Laser Intelligent Cleaning Technology and Equipment" (common key technologies) aims at the urgent demand for precision, green, intelligent and controllable new cleaning technology in aerospace equipment manufacturing and repair. This project is dedicated to understanding the multi-beam laser cleaning multi-field coupling mechanism, and breaking key technologies such as cooperative control of high energy high repetition rate nanosecond laser with multi-dimensional gain, residue location identification and path planning on complex surfaces, multi-beam splicing and energy control in ultra-wide format. At the same time, the research on high energy high frequency nanosecond pulsed laser, high efficient and high quality cleaning mechanisms and key technology, and ultra-wide format cleaning process and equipment are carried out. Finally, the research results will enable some typical applications for removing thermal control coatings from spacecraft surfaces and paint from aircraft radome surfaces.