Abstract: Due to the influence of material, fabrication technology and so on, blind-pixels exist on infrared focal plane array detectors. It reduces the infrered image quality and object detection capability, improves the object inveracious rate. Effective blind-pixels detection for infrared image process is an important development issue. Based on the analysis of the model for the effective pixel corrected response, the approach was proposed that, when the corrected response was uniform, the means (MEAN) and the standard deviation (STD) were both normal distributed random variables for all effective pixels. Through adaptive projective decomposition of MEAN and STD histograms, the MEAN and STD distribution range of effective pixel could be effectively estimated, and the detection rule for blind-pixel was got finally. The experimental result by applying real infrared image shows the proposed method for IRFPA blind-pixel detection is scientific and effective.