Abstract: In order to effectively detect the information of the abnormal heat inside the body, based on Fourier's law and the law of conservation of energy, a heat transfer differential equation with a spherical heat was established. Then the differential equation through the surface isotherm distribution was solved to obtain the relationship between the surface temperature distribution and the depth, size and temperature of the inner abnormal heat. Thus the spherical abnormal heat transfer model including the body surface temperature distribution and globular heat was established. Afterward the finite element analysis software COMSOL was used to simulate the model with numerical analysis. At the same time, the infrared thermal imager was used to collect the temperature distribution of the solid model surface, and then the internal heat source information was obtained by solving the differential equation. In the end, comparing the actual inner abnormal heat information with the information from the analysis of simulation and actual analysis, both the results and the actual error are in millimeters.