Abstract: The calculation of missile plume flow field provides basic data for that of the infrared radiation field. The formation of missile plume flow field was mainly studied, and the model of plume flow field was bulit according to the theory of combustion, fluid mechanics, gas dynamics, and considering the chemical reaction of combustion in the combustion chamber, the key parameters of flow field: velocity, temperature and pressure fields of data were given by combining Gambit and Fluent. The result whose residual was less than 1e-5 was obtained after more than 2 000 times iteration in Fluent. Velocity and pressure fields were in line with the actual situation, the temperature field's calculation error was 2%. The results show that the plume flow model can reflect the main features of flow field plume, and it can quickly provide the data results which the designer wants to get. It's able to provide basic data for the calculation of missile plume infrared characteristics, improve the accuracy of the plume, and save simulation time.