Abstract: In order to satisfy the requirements of infrared detector that can penetrate in visible and 3-5 m double wave bands, be reflected in 3 m wave band, optical diamond was selected as infrared window material to protect infrared detector from laser beams. V2O5 film with thermally induced phase transition properties was selected as anti-laser blinding coating. ZnS and YbF3 were chosen as high and low index of refraction materials respectively. Infrared anti-reflective coating applied on laser protection was designed based on design theory of films and optimized by TFCalc. Anti-reflective coatings were fabricated by ion assisted deposition and V2O5 coating was fabricated on anti-reflective coatings by using the method of magnetron sputtering. The surface topography and roughness of optical thin film were tested by scanning probe microscope and the infrared spectra was tested and analyzed. The results meet the requirements of design and application.