Abstract: Due to the non-uniformity of uncooled infrared focal plane arrays (IRFPA) shifting along with the variation of the application surrounding temperature, correction parameter must be updated frequently otherwise the correction quality would be degraded. Based on binary nonlinear non-uniformity theory model, a novel non-uniformity correction method considering surrounding temperature compensation was proposed. The implement procedure was described in detail. This approach takes into account both the responsive nonlinearity under the large dynamic range and the influence of surrounding temperature changes for non-uniformity. Quantitative test and comparison were performed among several correction technologies. Experimental test results show that the remainder non-uniformity corrected by proposal algorithm is less than 0.017%. This technique reduces the correction error largely. Real-time imaging indicates this method improve the image quality clearly. Furthermore, extends the application range of non-uniformity correction technology.