Abstract: The influence of atmospheric turbulence on aim precision of ground-to-satellite was theoretically investigated in this paper. First of all, the definition of aim precision of ground-to-satellite laser was proposed in the atmospheric turbulence. Secondly, the aim precision of ground-to-satellite laser under the different launch parameters was numerically simulated by solving the parabolic equation of laser atmospheric propagation with multi-phase screen method. The results show that the aim precision of ground-to-satellite laser is proportional to the launch aperture of laser, but inversely proportional to the divergence angle of laser. The power and power density at the satellite's pupil were lastly calculated under the different aim precisions. The research conclusion can provide the theoretical basis and data reference for carrying out the countermeasure experiment of ground-to-satellite.