Abstract: A real-time data acquisition and processing technique of long linear infrared detectors which was realized on FPGA was introduced. A method of rearrangement of parity line detectors was illustrated with FPGA. By illustrating traditional 2D linear extrapolation blind pixel detection and restoration algorithm, an improved one, which well fitted the case when several blind pixels bordered each other and reduced the detection and restoration efficiency, was proposed. Non-uniformity correction(NUC) of detectors was implemented inside FPGA by referring to the proposed data processing organization. The experiment results show that the mentioned data acquisition and processing techniques can raise data transmission efficiency to a great degree. Meanwhile, it possesses the characteristic of well real-time and can be widely applied in related area.