Abstract: An optic-electronic disturbance experiment was done since there is no same proportion long distance experiment validation in the mid-infrared optic-electronic disturbance research currently. The laser power was 10 W, the wavelength was 5.4 m, the camera of mid-infrared wavelength with the disturbance distance of 15 km was disturbed by the mid-infrared laser in this experiment. Many group experiments were done under some different conditions. A lot of laser disturbance image under the conditions were gained. The laser power density could be calculated using the data. The camera would not distill aim when the laser power being 5.6 W from these images, in this condition the radiation angle of the laser was 15 mrad, the distance between the laser and camera was 15 km, the focus of the mid-infrared camera was 384 mm, the visibility was 0.452 and the power density was 0.064 mW/m2. This experiment can validate the 15 km long distance mid-infrared laser disturbance to missile camera system being coming true using now domestic mature technology. These experiment data can sustain the adding research about the parameter in reversing deducing and confirm in exactitude atmosphere permeation rate mode and mid-infrared optic-electronic confrontation evaluation mode.