Picosecond infrared multi-wavelength Raman laser which adopted multi-pulse pumped KGW crystal was reported. A mathematical model was developed to investigate the effect of multi-pulse burst pumping regime on the vibrational mode of the Raman active molecule. The simulated results show that the response oscillation of the Raman active molecule to the multi-pulse burst pumping regime is more active and durable compared with the traditional single pulse pumping regime, which promotes the weakened molecule oscillation to return the natural frequency multiple times. The enhancement effect is beneficial to improve the Raman gain, reduce the Raman threshold, and increase the Raman conversion efficiency. During the experiment of picosecond multi-pulse pump KGW Raman crystal, the three-pulse burst pumping regime improves the Raman gain more than two times, reduces the threshold of stimulated Raman scattering more than 50%, and increases the Raman conversion efficiency more than 16% for 768 cm–1 Raman mode and 22% for 901 cm–1 Raman mode. Based on the three-pulse burst pumping regime, a 1 kHz mJ-level picosecond infrared multi-wavelength Raman laser was designed, which achieved the pulse energy of 1.39 mJ, the maximum Raman conversion efficiency of 29.6% for the 768 cm–1 vibrational mode of KGW, and the pulse energy of 1.38 mJ, the maximum Raman conversion efficiency of 25.7% for the 901 cm–1 vibrational mode of KGW. In addition, the Raman laser can radiate up to eight infrared Raman lines simultaneously for both the two vibrational modes of the KGW crystal, which covers the range of 800–1 700 nm.